{"id":1,"date":"2023-11-08T09:43:00","date_gmt":"2023-11-08T09:43:00","guid":{"rendered":"https:\/\/fund.southampton.ac.uk\/innovation\/?p=1"},"modified":"2024-04-25T12:42:49","modified_gmt":"2024-04-25T12:42:49","slug":"article-5","status":"publish","type":"post","link":"https:\/\/fund.southampton.ac.uk\/innovation\/blog\/2023\/11\/08\/article-5\/","title":{"rendered":"First-of-its-kind trial hopes to improve survival rates for bladder cancer"},"content":{"rendered":"\n<main class=\"wp-block-group alignfull is-layout-flow wp-container-core-group-is-layout-719178b4 wp-block-group-is-layout-flow\" style=\"margin-top:0;margin-bottom:0;padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\">\n<div class=\"wp-block-group has-base-2-color has-custom-mif-dark-green-background-color has-text-color has-background has-link-color wp-elements-1 has-global-padding is-layout-constrained wp-container-core-group-is-layout-829f05ab wp-block-group-is-layout-constrained\" style=\"margin-top:0;margin-bottom:var(--wp--preset--spacing--40);padding-top:0;padding-right:0;padding-bottom:0\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-a16e6d8b wp-block-columns-is-layout-flex\" style=\"padding-right:0;padding-left:0\">\n<div class=\"wp-block-column is-vertically-aligned-center is-layout-flow wp-container-core-column-is-layout-bf759c5d wp-block-column-is-layout-flow\" style=\"padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)\"><h1 style=\"font-size:clamp(2.089rem, 2.089rem + ((1vw - 0.2rem) * 2.076), 3.75rem);margin-bottom:var(--wp--preset--spacing--30)\" class=\"has-link-color wp-elements-2 wp-block-post-title has-text-color has-base-2-color\">First-of-its-kind trial hopes to improve survival rates for bladder cancer<\/h1>\n\n\n<div class=\"wp-block-group is-horizontal is-layout-flex wp-block-group-is-layout-flex\" style=\"margin-top:0;margin-bottom:0\">\n<p class=\"has-base-2-color has-text-color has-link-color wp-elements-3 wp-container-content-722fc917 wp-block-paragraph\" style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.469), 1.25rem);font-style:normal;font-weight:600\"><strong>Date<\/strong>:<\/p>\n\n\n<div style=\"font-size:clamp(0.875rem, 0.875rem + ((1vw - 0.2rem) * 0.469), 1.25rem)\" class=\"has-link-color wp-elements-4 wp-block-post-date has-text-color has-base-2-color\"><time datetime=\"2023-11-08T09:43:00+00:00\">November 8, 2023<\/time><\/div><\/div>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-container-core-column-is-layout-c03d89fc wp-block-column-is-layout-flow\" style=\"padding-top:0;padding-right:0;padding-bottom:0;padding-left:0\"><figure style=\"padding-top:0;padding-bottom:0;padding-left:0;padding-right:0;margin-bottom:0\" class=\"alignright wp-block-post-featured-image\"><img decoding=\"async\" width=\"480\" height=\"355\" src=\"https:\/\/fund.southampton.ac.uk\/innovation\/wp-content\/uploads\/sites\/2\/2024\/04\/Jenny-Down-web.jpg\" class=\"attachment-post-thumbnail size-post-thumbnail wp-post-image\" alt=\"\" style=\"border-radius:0px;aspect-ratio:16\/9;width:100%;height:100%;object-fit:contain;\" srcset=\"https:\/\/fund.southampton.ac.uk\/innovation\/wp-content\/uploads\/sites\/2\/2024\/04\/Jenny-Down-web.jpg 480w, https:\/\/fund.southampton.ac.uk\/innovation\/wp-content\/uploads\/sites\/2\/2024\/04\/Jenny-Down-web-300x222.jpg 300w\" sizes=\"(max-width: 480px) 100vw, 480px\" \/><\/figure><\/div>\n<\/div>\n<\/div>\n<\/main>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>A major new trial, called the GUSTO trial, is being held jointly by the University of Southampton, Sheffield Teaching Hospitals NHS Foundation, and the University of Leeds. <\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It will seek to establish if treatments for muscle-invasive bladder cancer, one of the most common and expensive-to-treat cancers, can be modified to different genetic subtypes known to cause the disease. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Current standard treatments for patients with cancer of the bladder wall involve chemotherapy, before either surgery to remove the bladder or radiotherapy.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Until now, it has not been possible to say how individuals will respond to this treatment. However, new research suggests that different genetic causes of bladder cancers may respond differently to different treatments. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">To read the full story, click <a href=\"https:\/\/www.southampton.ac.uk\/news\/2023\/11\/gusto-bladder-cancer.page\">here<\/a>. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Smart treatments matched to the biology of cancers could save lives.<\/p>\n","protected":false},"author":7,"featured_media":432,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_uag_custom_page_level_css":"","footnotes":""},"categories":[34],"tags":[22,21],"class_list":["post-1","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cancer","tag-cancer","tag-research"],"acf":[],"mb":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ 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